Reference range is relative; many factors come into play when interpreting findings of serial serum chemistries.
Time after time. Frustrated by what is really significant when performing serum chemistry profiles? At CVC Kansas City, Craig Ruaux, BVSc (Hons), PhD, MACVSc, DACVIM-SA, an associate professor of small animal internal medicine at Oregon State University’s College of Veterinary Medicine, discussed several reasons for variability in serum chemistry profile results in his lecture titled, “Let’s just monitor it: The pitfalls and problems with serial serum chemistries.” He said these reasons can be divided into three different categories:
Pre-analytical
- Fasting
- Venipuncture technique
- Centrifugation
- Storage
- Shipping
Analytical
- Interassay variation
- Assay operator
- Equipment
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